The Role of Acsl1 and Aldh2 in the Increased Risk for Liver Cancer in Offspring of Obese Mothers

Frontiers in Medicine

article

Beat Moeckli¹  Stéphanie Lacotte¹  Christian Toso¹ 

[1] Division of Visceral Surgery, Department of Surgery, Geneva University Hospitals;Hepatology and Transplantation Laboratory, Division of Visceral Surgery, Department of Surgery, Faculty of Medicine, University of Geneva

关键词: hepatocellular carcinoma;    maternal obesity;    origin of disease and health;    microbiota;    epigenetics;   

DOI  :  10.3389/fmed.2022.907028

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

The obesity rate continues to increase and already exceeds 30% in many regions of the world (1). This truly global phenomenon affects women of childbearing age particularly and thus more and more children are born to obese mothers every year (2). Large-scale epidemiological studies have shown that maternal obesity has deleterious effects on offspring health such as increased risk for obesity, liver steatosis and even certain types of cancers (3–5).

【 授权许可】

CC BY