Impact of Isolation Time of COVID-19 Patients in Intensive Care Unit on Healthcare Workers Contamination and Nursing Care Intensity

Frontiers in Medicine

article

Denis Doyen¹  Lucas Morand¹  Mathieu Jozwiak¹  Didac Aurenche Mateu¹  Clément Saccheri¹  Hervé Hyvernat¹  Marion Cremoni²  Vesna Brglez²  Nicolas Bèle⁵  Gilles Bernardin¹  Barbara Seitz-Polski²  Jean Dellamonica¹ 

[1] Service de Médecine Intensive Réanimation, Centre Hospitalier Universitaire de Nice, Hôpital Archet 1;UR2CA – Unité de Recherche Clinique Côte d’Azur, Université Côte d’Azur;LP2M – CNRS Laboratoire de Physiomédecine Moléculaire, Université Côte d’Azur;Laboratoire d’Immunologie, Centre Hospitalier Universitaire de Nice, Hôpital Archet 1;Centre Hospitalier Intercommunal de Fréjus Saint-Raphaël

关键词: COVID-19;    isolation;    healthcare workers;    contamination;    nursing care;    adverse events;   

DOI  :  10.3389/fmed.2022.824563

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Background The optimal isolation time of COVID-19 patients in intensive care unit (ICU) is debated. We investigated the impact of two different COVID-19 patient isolation time strategies on healthcare workers (HCW) contamination, intensity of nursing care and potential associated adverse events. Methods We prospectively included all consecutive COVID-19 patients and HCW in our ICU in the first two pandemic waves (March to May 2020 and August to November 2020). Specific isolation measures for COVID-19 patients were released after two negative RT-PCR assays in the first wave and 14 days after the onset of symptoms in the second wave. Contamination of HCW was assessed at the end of each pandemic wave by combining both a RT-PCR assay and a serological test. Results Overall, 117 COVID-19 patients and 73 HCW were included. Despite an earlier release from isolation after ICU admission in the second than in the first wave [6 (4–8) vs. 15 (11–19) days, p < 0.01], the proportion of HCW with a positive serological test (16 vs. 17%, p = 0.94) or with a positive RT-PCR assay (3 vs. 5%, p = 0.58) was not different between the two waves. Although a lower nurse-to-bed ratio, the intensity of nursing care was higher in the second than in the first wave. A longer isolation time was associated with accidental extubation (OR = 1.18, 95%CI:1.07–1.35, p = 0.005) but neither with ventilator-associated pneumonia nor with dysglycemia. Conclusion A shorter isolation time of COVID-19 patients in ICU was not associated with higher HCW contamination, while a longer isolation time seemed to be associated with higher accidental extubation.

【 授权许可】

CC BY