How to Deal With Vaccine Breakthrough Infection With SARS-CoV-2 Variants

Frontiers in Public Health

article

Ying Guo¹  Jun Meng²  Caide Liu³  Guosheng Chen⁴  Yuhua Chi³  Shiliang Zheng³  Haixia Wang⁵ 

[1] Department of Endocrinology, Affiliated Hospital of Weifang Medical University;Department of Respiratory Medicine, Affiliated Hospital of Weifang Medical University;Department of General Practice, Affiliated Hospital of Weifang Medical University;General Practice Teaching and Research Section, Weifang Medical University;Department of Blood Transfusion, Affiliated Hospital of Weifang Medical University

关键词: SARS-CoV-2;    variants;    breakthrough;    infection;    Delta;    virulent strains;   

DOI  :  10.3389/fpubh.2022.842303

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Novel Coronary Pneumonia is the most infectious disease with the highest number of morbidity and mortality in 100 years. Despite aggressive and effective COVID-19 prevention and control measures, countries have been unable to stop its outbreaks. With the widespread use of vaccines, the occurrence of COVID-19 has declined markedly. April 21, 2021, New York scholars reported Vaccine Breakthrough Infections with SARS-CoV-2 Variants, which immediately attracted widespread attention. In this mini-review, we focus on the characteristics of SARS-CoV-2 and its mutant strains and vaccine breakthrough infections. We have found that outbreaks of vaccine-breaking SARS-CoV-2 Delta infections in many countries are primarily the result of declining vaccine-generated antibody titers and relaxed outbreak management measures. For this reason, we believe that the main response to vaccine-breaking infections with the SARS-CoV-2 variant is to implement a rigorous outbreak defense policy and vaccine application. Only by intensifying the current vaccination intensity, gradually improving the vaccine and its application methods, and strengthening non-pharmaceutical measures such as travel restrictions, social distancing, masking and hand hygiene, can the COVID-19 outbreak be fully controlled at an early date.

【 授权许可】

CC BY