Comparison of Clinical Features and Outcomes of Appendectomy in Elderly vs. Non-Elderly: A Systematic Review and Meta-Analysis

Frontiers in Surgery

article

Jie Yuan¹  Qingfeng Chen²  Weicong Hong¹  Lifeng Yu¹  Xuen Li¹ 

[1] Department of General Surgery, Longshan Hospital of Cixi City;Department of Gastrointestinal Surgery, Ningbo First Hospital, Ningbo Hospital of the Zhejiang University

关键词: appendectomy;    laparoscopic;    acute appendicitis;    elderly;    non-elderly;    young;    meta-analysis;    systematic review;   

DOI  :  10.3389/fsurg.2022.818347

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Background The objective of this study is to compare clinical and surgical outcomes of appendectomy among elderly and non-elderly subjects. Methods A systematic search was conducted on PubMed, Scopus, and Google academic databases. Studies, observational in design, that compared peri-and postoperative outcomes of appendectomy, in patients with acute appendicitis, between elderly and non-elderly/younger subjects were considered for inclusion. Statistical analysis was performed using STATA software. Results A total of 15 studies were included. Compared to non-elderly patients, those that were elderly had an increased risk of complicated appendicitis [relative risk (RR), 2.38; 95% CI: 2.13, 2.66], peritonitis [RR, 1.88; 95% CI: 1.36, 2.59], and conversion from laparoscopic to open appendectomy [RR, 3.02; 95% CI: 2.31, 3.95]. The risk of overall postoperative complications [RR, 2.59; 95% CI: 2.19, 3.06], intra-abdominal abscess [RR, 1.84; 95% CI: 1.15, 2.96], wound infection [RR, 3.80; 95% CI: 2.57, 5.61], and use of postoperative drainage [RR, 1.14; 95% CI: 1.09, 1.19] was higher among the elderly. The risk of readmission (30 days) [RR, 1.61; 95% CI: 1.16, 2.24] and mortality (30 days) [RR, 12.48; 95% CI: 3.65, 42.7] was also higher among elderly. Conclusions Findings suggest an increased risk of peri-and postoperative complications among elderly subjects undergoing appendectomy, compared to non-elderly subjects.

【 授权许可】

CC BY