Bionic Prostheses: The Emerging Alternative to Vascularised Composite Allotransplantation of the Limb

Frontiers in Surgery

article

Kavit R. Amin¹  James E. Fildes³ 

[1] Blond McIndoe Laboratories, Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre;Department of Plastic Surgery & Burns, Wythenshawe Hospital, Manchester University NHS Foundation Trust;The Ex-Vivo Research Centre CIC;The Healthcare Technologies Institute, School of Chemical Engineering, University of Birmingham

关键词: bionic limb;    hand transplant;    machine-human interface;    amputation;    vascularised composite allotransplantation;    bionic prostheses;   

DOI  :  10.3389/fsurg.2022.873507

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Twenty years have surpassed since the first vascularised composite allotransplantation (VCA) of the upper limb. This is an opportunity to reflect on the position of VCA as the gold standard in limb reconstruction. The paucity of recipients, tentative clinical outcomes, and insufficient scientific progress question whether VCA will remain a viable treatment option for the growing numbers of amputees. Bionic technology is advancing at a rapid pace. The prospect of widely available, affordable, safely applied prostheses with long-standing functional benefit is appealing. Progress in the field stems from the contributions made by engineering, electronic, computing and material science research groups. This review will address the ongoing reservations surrounding VCA whilst acknowledging the future impact of bionic technology as a realistic alternative for limb reconstruction.

【 授权许可】

CC BY