Risk Factors of Bone Nonfusion After Spinal Tuberculosis Debridement Bone Graft Fusion and Internal Fixation

Frontiers in Surgery

article

Zihan Wei¹  Ying Zhang¹  Sizhen Yang¹  Jiawen Ye¹  Xu Hu¹  Tian Li²  Tongwei Chu¹ 

[1] Department of Orthopedics, Xinqiao Hospital of Chongqing/Second Affiliated Hospital of Army Medical University;School of Basic Medicine, Fourth Military Medical University

关键词: spinal tuberculosis;    postoperative bone nonfusion;    risk factor;    retrospective study;    orthopeadics;   

DOI  :  10.3389/fsurg.2022.888148

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Objective To retrospectively analyze bone graft nonfusion risk factors in spinal tuberculosis patients after lesion debridement, bone graft fusion and internal fixation. Methods The clinical data of 131 patients who underwent spinal tuberculosis debridement, bone graft fusion and internal fixation in our hospital from March 2015 to March 2018 were retrospectively analyzed. The patients were divided into two groups according to bone fusion after the operation; there were 37 patients in the nonfusion group and 94 in the fusion group. The basic information and follow-up data of the patients were collected to evaluate the risk factors for bone graft nonfusion 1 year after surgery. Results The severity of osteoporosis in the nonfusion group was significantly greater than that in the fusion group ( p   1, p  < 0.05), while standard drug treatment for 1 year after surgery was a protective factor (OR < 1, p  < 0.05). Conclusion Spinal tuberculosis patients who had a long disease course, who underwent simple posterior debridement, or who had severe osteoporosis had a higher risk of bone graft nonfusion after surgery. Tuberculosis treatment is beneficial for the osseous fusion of the postoperative bone graft area.

【 授权许可】

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