Cardiac Doppler Parameters and Progress in Clinical Manifestation of Primary Lower Extremity Varicose Veins: A Prospective Study in China

Frontiers in Surgery

article

Jia Zhang¹  Zhoupeng Wu²  Qingbo Feng³  He Huang⁴  Yukui Ma² 

[1] West China Clinical Medical College, West China Hospital of Sichuan University;Department of Vascular Surgery, West China Hospital of Sichuan University;Department of Liver Surgery and Liver Transplantation Centre, West China Hospital of Sichuan University;Department of Cardiology, West China Hospital of Sichuan University

关键词: primary varicose veins;    cardiac Doppler;    cardiac haemodynamics;    CEAP;    age;   

DOI  :  10.3389/fsurg.2022.791598

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Objective To investigate the features of cardiac Doppler parameters in patients with primary lower extremity varicose veins in China. Materials and Methods We performed a prospective statistical analysis of cardiac Doppler parameters between 129 Chinese patients with varicose veins and normal controls. Furthermore, we evaluated the relationship between cardiac Doppler and the progress or severity of lower extremity varicose veins. Results Compared with normal controls, patients with primary varicose veins had significantly lower early mitral and tricuspid diastolic inflow and annular velocities (E- and e′-waves), significantly higher late mitral and tricuspid diastolic inflow and annular velocities (A- and a′-waves), significantly higher mitral systolic annular velocities (s′-wave), and significantly lower mitral and tricuspid E/A ratio. There was no significant association between deep venous reflux (DVR) of the lower extremities and cardiac Doppler parameters. The relationship between Clinical Etiological Anatomical Pathophysiological (CEAP) clinical class and cardiac Doppler parameters showed on that: In comparison with normal control, all cardiac Doppler parameters of C2 clinical class patients were basically unchanged, but the cardiac Doppler parameters of the C3 or higher CEAP class patients changed. Hence, we found a potential CEAP grade cut-off value (C3) linked to statistical changes in cardiac Doppler parameters. Conclusion Cardiac Doppler parameters in patients with primary varicose veins could indeed be different from those of normal people, especially for C3 class or higher CEAP clinical class patients. Therefore, for those patients, pre-operative echocardiography can be used to evaluate cardiac hemodynamic changes, but large-scale clinical promotion requires further large sample studies.

【 授权许可】

CC BY