Chronic Obstructive Pulmonary Disease: A Complex Comorbidity of Lung Cancer

Journal of Comorbidity

Review

Derek Grose¹  Robert Milroy² 

[1] Beatson West of Scotland Cancer Centre, Glasgow, Scotland, UK;Glasgow Royal Infirmary, Glasgow, Scotland, UK;

关键词: chronic obstructive pulmonary disease (COPD);    comorbidity;    inflammation;    lung cancer;    oxidative stress;    pulmonary;   

DOI  :  10.15256/joc.2011.1.5

 received in 2011-11-01, accepted in 2011-11-28,  发布年份 2011

来源: Sage Journals

【 摘 要 】

Chronic obstructive pulmonary disease (COPD) is a major burden throughout the world. It is associated with a significantly increased incidence of lung cancer and may influence treatment options and outcome. Impaired lung function confirming COPD is an independent risk factor for lung cancer. Oxidative stress and inflammation may be a key link between COPD and lung cancer, with numerous molecular markers being analysed to attempt to understand the pathway of lung cancer development. COPD negatively influences the ability to deliver radical treatment options, so attempts must be made to look for alternative methods of treating lung cancer, while aiming to manage the underlying COPD. Detailed assessment and management plans utilising the multidisciplinary team must be made for all lung cancer patients with COPD to provide the best care possible.

【 授权许可】

CC BY-NC   
© 2011 SAGE Publications Ltd

【 图 表 】

Figure 2.