Breast Cancer: Basic and Clinical Research | |
Adipose-Derived Stem Cells in Novel Approaches to Breast Reconstruction: Their Suitability for Tissue Engineering and Oncological Safety | |
Review | |
Michael J Kerin1  Donald Courtney1  Niamh O’Halloran1  Aoife J Lowery2  | |
[1] Discipline of Surgery, Lambe Institute for Translational Research, National University of Ireland, Galway, Galway, Ireland;Graduate Entry Medical School, University of Limerick, Limerick, Ireland; | |
关键词: Breast reconstruction; mastectomy; adipose-derived stem cells; tissue engineering; adipose tissue engineering; breast cancer; | |
DOI : 10.1177/1178223417726777 | |
received in 2017-04-27, accepted in 2017-07-13, 发布年份 2017 | |
来源: Sage Journals | |
【 摘 要 】
Adipose-derived stem cells (ADSCs) are rapidly becoming the gold standard cell source for tissue engineering strategies and hold great potential for novel breast reconstruction strategies. However, their use in patients with breast cancer is controversial and their oncological safety, particularly in relation to local disease recurrence, has been questioned. In vitro, in vivo, and clinical studies using ADSCs report conflicting data on their suitability for adipose tissue regeneration in patients with cancer. This review aims to provide an overview of the potential role for ADSCs in breast reconstruction and to examine the evidence relating to the oncologic safety of their use in patients with breast cancer.
【 授权许可】
CC BY
© The Author(s) 2017
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202212207731667ZK.pdf | 675KB | download | |
Figure 10. | 162KB | Image | download |
Table 1. | 975KB | Table | download |
Figure 1. | 602KB | Image | download |
Figure 5. | 306KB | Image | download |
Figure 7. | 91KB | Image | download |
【 图 表 】
Figure 7.
Figure 5.
Figure 1.
Figure 10.
【 参考文献 】
- [1]
- [2]
- [3]
- [4]
- [5]
- [6]
- [7]
- [8]
- [9]
- [10]
- [11]
- [12]
- [13]
- [14]
- [15]
- [16]
- [17]
- [18]
- [19]
- [20]
- [21]
- [22]
- [23]
- [24]
- [25]
- [26]
- [27]
- [28]
- [29]
- [30]
- [31]
- [32]
- [33]
- [34]
- [35]
- [36]
- [37]
- [38]
- [39]
- [40]
- [41]
- [42]
- [43]
- [44]
- [45]
- [46]
- [47]
- [48]
- [49]
- [50]
- [51]
- [52]
- [53]
- [54]
- [55]
- [56]
- [57]
- [58]
- [59]
- [60]
- [61]
- [62]
- [63]
- [64]
- [65]
- [66]
- [67]
- [68]
- [69]
- [70]
- [71]
- [72]
- [73]
- [74]
- [75]
- [76]
- [77]
- [78]
- [79]
- [80]
- [81]
- [82]
- [83]
- [84]
- [85]
- [86]
- [87]
- [88]
- [89]
- [90]
- [91]
- [92]
- [93]
- [94]
- [95]
- [96]
- [97]
- [98]
- [99]
- [100]
- [101]
- [102]
- [103]
- [104]
- [105]
- [106]
- [107]
- [108]
- [109]
- [110]
- [111]
- [112]
- [113]
- [114]
- [115]
- [116]
- [117]
- [118]
- [119]
- [120]
- [121]
- [122]
- [123]
- [124]
- [125]
- [126]
- [127]
- [128]
- [129]
- [130]
- [131]
- [132]
- [133]
- [134]
- [135]
- [136]
- [137]
- [138]
- [139]
- [140]
- [141]
- [142]
- [143]
- [144]
- [145]
- [146]
- [147]
- [148]
- [149]
- [150]
- [151]
- [152]
- [153]
- [154]
- [155]
- [156]
- [157]
- [158]
- [159]
- [160]
- [161]
- [162]
- [163]
- [164]
- [165]
- [166]
- [167]
- [168]
- [169]
- [170]
- [171]
- [172]
- [173]
- [174]
- [175]
- [176]
- [177]
- [178]
- [179]
- [180]
- [181]
- [182]
- [183]
- [184]
- [185]
- [186]
- [187]
- [188]
- [189]
- [190]
- [191]
- [192]
- [193]
- [194]
- [195]
- [196]
- [197]
- [198]
- [199]
- [200]
- [201]
- [202]
- [203]
- [204]
- [205]
- [206]
- [207]