Tissue Engineering and the Challenges Within

Cell Transplantation

Article

Sara L. Wargo¹  Thangappan Ravi Kumar¹  Alan J. Russell¹ 

[1] McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA;

关键词: Tissue engineering;    Biomaterials;    Cell source;    Gradient scaffolds;   

DOI  :  10.3727/000000006783982403

来源: Sage Journals

【 摘 要 】

Researchers face many challenges, both scientific and societal, in the field of tissue engineering. Herein we discuss the challenges in material design, selection of therapeutic cell source, the in vitro culturing of cells and materials, and finally the integration of the cultured construct into the body. We focus special attention on a new approach to the design of a biomaterial that would bridge synthetic and biologic materials seamlessly. The scaffolds we have developed serve as a transitional material between biotic and abiotic systems.

【 授权许可】

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