Doege–Potter Syndrome and Hypoglycemia associated with Solitary Fibrous Tumor of the Pleura: Two Case Reports

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine

Case Report

Valeria Zúñiga-Restrepo¹  Liliana Fernández-Trujillo²  Jhon E Bolaños³  Julián Giraldo³  Carolina Álvarez³  Bladimir Pérez⁴  Luz F Sua⁴  Mauricio Velásquez⁵ 

[1] Clinical Research Center, Fundación Valle del Lili, Cali, Colombia;Department of Internal Medicine, Pulmonology Service, Interventional Pulmonology, Fundación Valle del Lili, Cali, Colombia;Faculty of Health Sciences, Universidad Icesi, Cali, Colombia;Faculty of Health Sciences, Universidad Icesi, Cali, Colombia;Faculty of Health Sciences, Universidad Icesi, Cali, Colombia;Department of Pathology and Laboratory Medicine, Fundación Valle del Lili. Cali, Colombia;Faculty of Health Sciences, Universidad Icesi, Cali, Colombia;Department of Surgery, Thoracic Surgery Service, Fundación Valle del Lili, Cali, Colombia;

关键词: Pleura;    pleural tumor;    solitary fibrous tumor;    thoracic surgery;    hypoglycemia;   

DOI  :  10.1177/1179548420964759

 received in 2020-04-29, accepted in 2020-09-17,  发布年份 2020

来源: Sage Journals

【 摘 要 】

Solitary fibrous tumors of the pleura (SFTP) are rare mesenchymal neoplasms that originate from mesenchymal growth in the pleura, tend to be single tumors, usually have an indolent course and show nonspecific symptoms. SFTP can be often diagnosed from an incidental finding of a single mass in the thorax and should be confirmed by biopsy and immunohistochemistry. A minority of cases may present Doege–Potter syndrome (DPS, episodes of refractory hypoglycemia) associated with production of insulin-like growth factor 2 (IGF-2). Both SFTP and DPS are rare occurrences with less than 2000 cases reported worldwide. The curative treatment is tumor resection. Two cases of patients with DPS caused by SFTP are presented below.

【 授权许可】

CC BY-NC   
© The Author(s) 2020

【 图 表 】

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