Allergic Subjects Have More Numerous Respiratory Infections and Severe Gastrointestinal Infections Than Non-Allergic Subjects: Preliminary Results

European Journal of Inflammation

Diseases and Inflammation

G.L. Marseglia¹  G. Ciprandi²  R.M. Troisi³  I. Cirillo³ 

[1] Dipartimento di Scienze Pediatriche Università di Pavia, IRCCS Policlinico San Matteo, Pavia, Italy;Giorgio Ciprandi, M.D., Semeiotica Medica I, Dipartimento Patologie Immuno-endocrinologiche, Padiglione 3, Ospedale San Martino, Largo R. Benzi 10, 16132 Genoa, Italy, Tel: ++39 10 35338120 Fax: ++39 10 3537573, e-mail: ;Ospedale Marina Militare, La Spezia;

关键词: allergy;    respiratory infections;    gastrointestinal infections;    Th1 and Th2 cells;   

DOI  :  10.1177/1721727X0700500105

 received in 2006-07-17, accepted in 2007-01-18,  发布年份 2007

来源: Sage Journals

【 摘 要 】

Allergic disorders are characterized by Th2-polarization, thus physiological Th1-dependent mechanisms for fighting infectious diseases (ID) may be defective. This study aims at evaluating the number and duration of respiratory (RI) and gastrointestinal diseases (GI) in allergic and non-allergic subjects in a particular community: the crew of an operative warship consisting of 189 persons (171 males and 18 females). The study period lasted for 5 months during an operative mission. The number and duration (days) of RI and GI were evaluated. Allergic subjects experienced more numerous RI (p=0.0029) and more severe GI (p=0.0001) than non-allergic subjects. This preliminary study provides evidence that allergic subjects may have more numerous RI and prolonged GI than non-allergic subjects.

【 授权许可】

Unknown   
© 2007 SAGE Publications