Medical Treatment of Essential Tremor

Journal of Central Nervous System Disease

Review

Alex Rajput¹  Ali H. Rajput¹ 

[1] University of Saskatchewan, Canada.;Saskatoon Health Region, Canada.;

关键词: essential tremor;    medical treatment;    diagnosis;    pathophysiology;    drugs;    individualized treatment;   

DOI  :  10.4137/JCNSD.S13570

 received in 2013-11-04, accepted in 2014-03-12,  发布年份 2014

来源: Sage Journals

【 摘 要 】

Essential tremor (ET) is the most common pathological tremor characterized by upper limb action—postural tremor (PT)/kinetic tremor (KT). There are no specific neuropathological or biochemical abnormalities in ET. The disability is consequent to amplitude of KT, which may remain mild without handicap or may become disabling. The most effective drugs for sustained tremor control are propranolol and primidone. Symptomatic drug treatment must be individualized depending on the circumstances that provoke the tremor-related disability. Broad guidelines for treatment are discussed in this review. Patients may be treated intermittently only on stressful occasions with propranolol, clonazepam, or primidone monotherapy, or an alcoholic drink. Those with persistently disabling tremor need continued treatment.

【 授权许可】

CC BY-NC   
© 2014 SAGE Publications.

【 图 表 】

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