Journal of Central Nervous System Disease | |
Molecular Mechanism of Adult Neurogenesis and its Association with Human Brain Diseases | |
Article | |
He Liu1  Ni Song2  | |
[1] Department of Biology, Morosky College of Health Professions and Sciences, Gannon University, Erie, PA, USA.;Division of Health Sciences & Workforce Technology, Lamar State College-Orange, Orange, TX, USA.; | |
关键词: adult neurogenesis; molecular factors; human brain diseases; | |
DOI : 10.4137/JCNSD.S32204 | |
received in 2015-08-27, accepted in 2016-05-30, 发布年份 2016 | |
来源: Sage Journals | |
【 摘 要 】
Recent advances in neuroscience challenge the old dogma that neurogenesis occurs only during embryonic development. Mounting evidence suggests that functional neurogenesis occurs throughout adulthood. This review article discusses molecular factors that affect adult neurogenesis, including morphogens, growth factors, neurotransmitters, transcription factors, and epigenetic factors. Furthermore, we summarize and compare current evidence of associations between adult neurogenesis and human brain diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and brain tumors.
【 授权许可】
CC BY-NC
© 2016 SAGE Publications.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202212201071854ZK.pdf | 532KB | download | |
Figure 3. | 248KB | Image | download |
【 图 表 】
Figure 3.
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