Relative Adrenal Insufficiency in Cirrhotic Patients

Clinical Medicine Insights: Gastroenterology

Article

Georgios S. Germanidis¹  Olga I. Giouleme²  Sotirios N. Anastasiadis³  Themistoklis G. Vasiliadis³ 

[1] 1st Department of Internal Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, Greece.;2nd Prop. Clinic of Internal Medicine, Hippokration Hospital, Aristotle University of Thessaloniki, Greece.;3rd Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, Greece.;

关键词: cirrhosis;    liver failure;    adrenal insufficiency;    hepatoadrenal syndrome;   

DOI  :  10.4137/CGast.S18127

 received in 2014-06-29, accepted in 2014-10-12,  发布年份 2015

来源: Sage Journals

【 摘 要 】

Relative adrenal insufficiency (RAI) was demonstrated in patients with cirrhosis and liver failure. A relationship appears to exist between the severity of the liver disease and the presence of RAI. Neither the mechanism nor the exact prevalence of RAI is fully understood. There is though a hypothesis that low high-density lipoprotein (HDL) levels in this group of patients may be responsible for the insufficiency of cortisol. Several questions also arise about the way and the kind of cortisol (total cortisol, free cortisol, or even salivary cortisol) that should be measured. The presence of RAI in patients with cirrhosis is unquestionable, but still several studies should come up in order to properly define it and fully understand it.

【 授权许可】

CC BY-NC   
© 2015 SAGE Publications.