Relationship between Responses to Bronchodilation Testing and to Nasal Decongestion Testing in Patients with Allergic Rhinitis Alone

European Journal of Inflammation

Article

G.L. Marseglia¹  G. Ciprandi²  A. Pistorio³  M.A. Tosca⁴  I. Cirillo⁵ 

[1] Clinica Pediatrica, Foundation IRCCS San Matteo, University of Pavia, Pavia, Italy;Department of Internal Medicine, Azienda Ospedaliera Universitaria San Martino, Genoa;Epidemiology and Statistics Unit, IRCCS G. Gaslini, Genoa;Pneumology and Allergy Center, IRCCS G. Gaslini, Genoa;Pneumology and Allergy, Navy Medical Service, La Spezia;

关键词: allergic rhinitis;    bronchodilation;    decongestion test;    nasal obstruction;    rhinomanometry;    spirometry;   

DOI  :  10.1177/1721727X0900700305

 received in 2009-04-04, accepted in 2009-07-30,  发布年份 2009

来源: Sage Journals

【 摘 要 】

A remarkable relationship exists between upper and lower airways. Bronchial obstruction is a paramount feature of asthma as well as nasal obstruction of allergic rhinitis (AR). This study aims to evaluate the response to both bronchodilation and decongestion testing and their relationships in a large group of patients with moderate-severe persistent AR alone. Two hundred eleven patients with moderate-severe persistent AR were prospectively and consecutively evaluated. Clinical examination, skin prick test, spirometry, bronchodilation test, rhinomanometry, and decongestion test were performed on all patients. Seventeen subjects (8%) did not respond to any of the tests, 55 subjects (26.1%) were responders only to the decongestion test, 31 (14.7%) only to the bronchodilation test, and 108 subjects (51.2%) responded to both these tests. Longer AR duration was significantly associated with positive response to both tests (p<0.01). In conclusion, this study provides the first evidence that patients with moderate-severe persistent AR may frequently show reversibility to both bronchodilation and decongestion tests.

【 授权许可】

Unknown   
© 2009 SAGE Publications Ltd unless otherwise noted.