Prognostic factors associated with small for gestational age babies in a tertiary care hospital of Western Nepal: A cross‐sectional study

Health Science Reports

Santosh Pathak¹  Binod Kumar Gupta²  Sandeep Shrestha²  Nagendra Chaudhary²  Suresh Kumar Kalra²  Shree Narayan Yadav²  Imran Satia³  Om Prakash Kurmi³  Steven Sadhra⁴  Charlotte Emma Bolton⁵  Matthew Patel⁶ 

[1] Department of Pediatrics Chitwan Medical College Bharatpur Nepal;Department of Pediatrics Universal College of Medical Sciences Bhairahawa Nepal;Division of Respirology, Department of Medicine McMaster University Hamilton Ontario Canada;Institute of Clinical Sciences College of Medical and Dental Sciences, University of Birmingham Birmingham UK;NIHR Nottingham Biomedical Research Centre School of Medicine, University of Nottingham Nottingham UK;The Royal College of Surgeons in Ireland Dublin Ireland;

关键词: appropriate for gestational age;    household air pollution;    prognostic factors;    small for gestational age;   

DOI  :  10.1002/hsr2.250

来源: DOAJ

【 摘 要 】

Abstract Background Small for gestational age (SGA) is common among newborns in low‐income countries like Nepal and has higher immediate mortality and morbidities. Objectives To study the prevalence and prognostic factors of SGA babies in Western Nepal. Methods A cross‐sectional study (November 2016‐October 2017) was conducted in a tertiary care hospital in Western Nepal. Socio‐demographic, lifestyle factors including diet, and exposures including smoking and household air pollution in mothers who delivered newborns appropriate for gestational age (AGA), SGA and large for gestational age (LGA) were recorded. Logistic regression was carried out to find the odds ratio of prognostic factors after adjusting for potential confounders. Results Out of 4000 delivered babies, 77% (n = 3078) were AGA, 20.3% (n = 813) were SGA and 2.7% (n = 109) were LGA. The proportion of female‐SGA was greater in comparison to male‐SGA (n = 427, 52.5% vs n = 386, 47.5%). SGA babies were born to mothers who had term, preterm, and postterm delivery in the following proportions 70.1%, 19.3%, and 10.6%, respectively. The average weight gain (mean ± SD) by mothers in AGA pregnancies was 10.3 ± 2.4 kg, whereas in SGA were 9.3 ± 2.4 kg. In addition to low socioeconomic status (OR 1.9, 95% CI 1.1, 3.2), other prognostic factors associated with SGA were lifestyle factors such as low maternal sleep duration (OR 5.1, CI 3.6, 7.4) and monthly or less frequent meat intake (OR 5.0, CI 3.2, 7.8). Besides smoking (OR 8.8, CI 2.1, 36.3), the other major environmental factor associated with SGA was exposure to household air pollution (OR 5.4, 4.1, 6.9) during pregnancy. Similarly, some of the adverse health conditions associated with a significantly higher risk of SGA were anemia, oligohydramnios, and gestational diabetes. Conclusions SGA is common in Western Nepal and associated with several modifiable prognostic factors.

【 授权许可】

Unknown