Roflumilast is effective in reducing COPD related exacerbations and improving CAT score

Monaldi Archives for Chest Disease

Biagio Polla¹ 

[1] Respiratory Physiopathology and Anti-Smoke Center, “SS. Antonio e Biagio e Cesare Arrigo” Hospital, Alessandria;

关键词: Roflumilast;    COPD;    Case report;    Exacerbations;    Steroid therapy;   

DOI  :  10.4081/monaldi.2013.32

来源: DOAJ

【 摘 要 】

We present a case of a 85-year-old man who suffered from several chronic obstructive pulmonary disease (COPD) related exacerbations and hospitalizations. Traditional therapy, which also included intramuscular steroid therapy, did not help and caused several drug related adverse events. After yet another exacerbation followed by hospitalization at the intensive care unit, it was decided to start roflumilast treatment. In the year after beginning treatment, the patient did not experience any more exacerbations and his lung function also improved, as recorded by the COPD assessment test (CAT) score and improved forced expiratory volume in the first second (FEV1) value. In this patient roflumilast seems to be effective in reducing exacerbations, an important goal to be achieved in COPD patients.

【 授权许可】

Unknown