Advances in Regenerative Sports Medicine Research

Frontiers in Bioengineering and Biotechnology

Wei Su¹  Jiebo Chen¹  Jing Wang¹  Yamin Li¹  Junjie Xu¹  Kai Zhang²  Hai Lin²  Jia Jiang³  Jinzhong Zhao³  Jiangyu Cai⁴  Liren Wang⁴  Tonghe Zhu⁵ 

[1] Department of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China;National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China;Regenerative Sports Medicine Lab of the Institute of Microsurgery on Extremities, Shanghai Jiao Tong University Affiliated Sixth People’ Hospital, Shanghai, China;Regenerative Sports Medicine and Translational Youth Science and Technology Innovation Workroom, Shanghai Jiao Tong University School of Medicine, Shanghai, China;School of Chemistry and Chemical Engineering, Shanghai Engineering Research Center of Pharmaceutical Intelligent Equipment, Shanghai Frontiers Science Research Center for Druggability of Cardiovascular Non-Coding RNA, Institute for Frontier Medical Technology, Shanghai University of Engineering Science, Shanghai, China;

关键词: regenerative medicine;    sports medicine;    meniscus;    rotator cuff;    cartilage;    tendon-to-bone;   

DOI  :  10.3389/fbioe.2022.908751

来源: DOAJ

【 摘 要 】

Regenerative sports medicine aims to address sports and aging-related conditions in the locomotor system using techniques that induce tissue regeneration. It also involves the treatment of meniscus and ligament injuries in the knee, Achilles’ tendon ruptures, rotator cuff tears, and cartilage and bone defects in various joints, as well as the regeneration of tendon–bone and cartilage–bone interfaces. There has been considerable progress in this field in recent years, resulting in promising steps toward the development of improved treatments as well as the identification of conundrums that require further targeted research. In this review the regeneration techniques currently considered optimal for each area of regenerative sports medicine have been reviewed and the time required for feasible clinical translation has been assessed. This review also provides insights into the direction of future efforts to minimize the gap between basic research and clinical applications.

【 授权许可】

Unknown