Dietary Patterns and Progression of Impaired Kidney Function in Japanese Adults: A Longitudinal Analysis for the Fukushima Health Management Survey, 2011–2015

Nutrients

Hironori Nakano¹  Eri Eguchi¹  Hiromasa Ohira²  Tetsuya Ohira³  Enbo Ma³  Mitsuaki Hosoya³  Makoto Miyazaki³  Akira Sakai⁴  Hirooki Yabe⁴  Hitoshi Ohto⁴  Atsushi Takahashi⁴  Junichiro Kazama⁴  Masaharu Maeda⁴  Kenji Kamiya⁴  Michio Shimabukuro⁴  Seiji Yasumura⁴ 

[1] Department of Epidemiology, Fukushima Medical University School of Medicine, Fukushima 960-1295, Japan;Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima 960-1295, Japan;Health Promotion Centre, Fukushima Medical University, Fukushima 960-1295, Japan;Radiation Medical Science Centre for Fukushima Health Management Survey, Fukushima Medical University, Fukushima 960-1295, Japan;

关键词: chronic kidney disease;    dietary pattern;    eGFR;    Fukushima Health Management Survey;    proteinuria;    trajectory analysis;   

DOI  :  10.3390/nu13010168

来源: DOAJ

【 摘 要 】

To investigate associations between dietary patterns and the risk of impaired kidney function, we analyzed data from 14,732 participants (40–89 years) who completed the baseline diet questionnaire of The Fukushima Health Management Survey in 2011. The incidence of chronic kidney disease (CKD) (estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m² or proteinuria (≥1+ by dipstick test)) and annual changes in eGFR were assessed from 2012 to 2015. Three major dietary patterns were identified. The adjusted cumulative incidence ratio of the highest vs. lowest tertile of a vegetable diet scores was 0.90 (95% confidence interval (CI): 0.82, 1.00) for eGFR < 60 mL/min/1.73 m², 0.68 (95% CI: 0.52, 0.90) for proteinuria, and 0.88 (95% CI: 0.80, 0.97) for CKD (P for trend = 0.031, 0.007, and 0.005, respectively). The incident risk of CKD in the highest tertile of juice diet scores was 18% higher than the lowest tertile. The odds ratio of the highest vs. lowest tertile of vegetable diet scores was 0.85 (95% CI: 0.75, 0.98) in the rapidly decreasing eGFR group (P for trend = 0.009). We did not observe significant associations for the meat dietary pattern. A Japanese vegetable diet could reduce the risk of developing impaired kidney function and CKD.

【 授权许可】

Unknown