Comorbidities associated with Sjögren's syndrome: Results from the Nationwide Inpatient Sample.

Translation

Abhishek Deshpande¹  Boyd M. Koffman²  Terah Koch³  Ibtisam Al-Hashimi⁴  Sadik A. Khuder⁵ 

[1] Case Western Reserve University School of Medicine, Cleveland OH 44106;Department of Neurology, University of Toledo Health Science Campus, Toledo, OH 43614;Nationwide Children's Hospital, Columbus, OH 43205;Texas A&M University Baylor College of Dentistry, Dallas, TX 75246;University of Toledo Health Science Campus, Toledo, OH 43614;

关键词: Sjögren’s syndrome;    autoimmune diseases;    comorbidities;    HCUP data;   

DOI  :  10.46570/utjms.vol1-2014-74

来源: DOAJ

【 摘 要 】

Although multiple comorbidities associated with Sjögren’s syndrome (SS) have been reported, reliable data regarding the prevalence of specific comorbidities among patients with SS remain sparse. In this study, we investigated the prevalence and risk for a broad spectrum of medical conditions among patients with SS in the United States. The Health Cost and Utilization Project (HCUP) Nationwide Inpatient Sample (NIS) data was utilized in order to investigate 29 different comorbidities among SS patients. Between the years 2007 to 2009 there were 19,127 admissions with SS listed as principal diagnosis (1.3%) and secondary diagnosis (98.7%). Compared with 57,381 controls, SS patients had significantly higher prevalence of lymphoma (OR 1.6), valvular disease (OR 1.42), congestive heart failure (OR 1.28), hypothyroidism (OR 1.24), paralysis (OR 1.24), deficiency anemia (OR 1.16), depression (OR 1.18), neurological disorders (OR 1.17), and chronic pulmonary disease (OR 1.07). SS is associated with substantial medical conditions that may impact morbidity and mortality as well as quality of life for individuals suffering from SS.

【 授权许可】

Unknown