Specifically Regional Cerebral Hypoperfusion in a Case of Highly Suspected Sporadic Creutzfeldt-Jakob Disease on 99mTc-ECD SPECT/CT with Easy Z-Score Imaging System Analysis

Diagnostics

Ming-Hui Yang¹  Hung-Pin Chan²  Daniel Hueng-Yuan Shen²  Shun-Chieh Chen²  Hung-Yen Chan² 

[1] Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung 813414, Taiwan;Department of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813414, Taiwan;

关键词: ^99mTc-ECD brain SPECT;    cerebral hypoperfusion;    Creutzfeldt-Jakob Disease;    MRI;    SPECT/CT;   

DOI  :  10.3390/diagnostics12020437

来源: DOAJ

【 摘 要 】

Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly-progressive dementing illness, the challenge of diagnosis during life. We presented a 78-year-old woman reported stupor, right facial palsy, and fluctuations in consciousness. ^99mTc-ECD brain SPECT/CT with eZIS analysis revealed significant decreased regional cerebral blood flow mainly in specific regions of Alzheimer’s disease as the published article reported with involving frontal region. Brain DWI MRI increased signal intensities corresponding to similar location of ^99mTc-ECD brain SPECT/CT. In this case, we reported the pattern of decreased rCBF may correlate to rapidly progressive dementia and associated neurodegenerative symptoms of the highly suspected sCJD patient.

【 授权许可】

Unknown