Upper Limb Robotic Rehabilitation for Patients with Cervical Spinal Cord Injury: A Comprehensive Review

Brain Sciences

Salvatore Petrozzino¹  Monica Sicari¹  Michele Senatore²  Stefano Mazzon³  Matteo Paci⁴  Giuseppe La Rosa⁵  Claudio Marcello Solaro⁶  Silvia Sterzi⁷  Sandra Miccinilli⁷  Federica Bressi⁷  Stefano Mazzoleni⁸  Paolo Benanti⁹  Alessandro Picelli^1,10  Marialuisa Gandolfi^1,10  Francesco Draicchio^1,11  Stefano Gargano^1,12  Silvia Galeri^1,13  Irene Aprile^1,14  Emanuela Casanova^1,15  Alberto Battistini^1,15  Dario Marino^1,16  Giovanni Morone^1,17  Alex Martino Cinnera^1,17  Vincenzo Falabella^1,18  Giuseppe Turchetti^1,19  Maurizio Petrarca^2,20  Francesca Gimigliano^2,21  Mauro Grigioni^2,22  Daniele Giansanti^2,22  Luca Perrero^2,23  Sofia Straudi^2,24  Serena Filoni^2,25  Enrico Castelli^2,26  Marco Invernizzi^2,27  Lorenzo Lippi^2,27  Alessandro de Sire^2,28  Federico Posteraro^2,29  Michela Agostini^3,30  Paolo Boldrini^3,31  Donatella Bonaiuti^3,31  Franco Molteni^3,32 

[1] A.O.U. Città della Salute e della Scienza di Torino, 10126 Turin, Italy;AITO (Associazione Italiana Terapisti Occupazionali), 00136 Rome, Italy;AULSS6 (Unique Sanitary Local Company) Euganea Padova, Rehabilitation Department, 35128 Padua, Italy;AUSL (Unique Sanitary Local Company), 50123 Florence, Italy;C.S.R.—Consorzio Siciliano di Riabilitazione, 95123 Catania, Italy;CRRF “Mons. Luigi Novarese”, 13040 Moncrivello, Italy;Campus Bio-Medico University Hospital, University of Rome, 00128 Rome, Italy;Department of Electrical and Information Engineering, Politecnico di Bari, 70125 Bari, Italy;Department of Moral Theology, Pontifical Gregorian University, 00187 Rome, Italy;Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37129 Verona, Italy;Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL, Monte Porzio Catone, 00185 Rome, Italy;Fondazione Don Carlo Gnocchi, 10143 Torino, Italy;IRCCS Fondazione Don Carlo Gnocchi, 20148 Milan, Italy;IRCCS Fondazione Don Carlo Gnocchi, 50123 Florence, Italy;IRCCS Istituto delle Scienze Neurologiche di Bologna, UOC Medicina Riabilitativa e Neuroriabilitazione, 40139 Bologna, Italy;IRCCS Neurolysis Center “Bonino Pulejo”, 98124 Messina, Italy;IRCCS Santa Lucia Foundation, 00179 Rome, Italy;Italian Federation of Persons with Spinal Cord Injuries (Faip Onlus), 00195 Rome, Italy;Management Institute, Sant’Anna School of Advanced Studies, 56127 Pisa, Italy;Movement Analysis and Robotics Laboratory MARlab, IRCCS Bambino Gesù Children’s Hospital, 00163 Rome, Italy;Multidisciplinary Department of Medicine for Surgery and Orthodontics, University of Campania “Luigi Vanvitelli”, 80138 Naples, Italy;National Center for Innovative Technologies in Public Health, Italian National Institute of Health, 00161 Rome, Italy;Neurorehabilitation Unit, Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, 15121 Alessandria, Italy;Neuroscience and Rehabilitation Department, Ferrara University Hospital, 44121 Ferrara, Italy;Padre Pio Foundation and Rehabilitation Center, San Giovanni Rotondo 71013, Italy;Paediatric Neurorehabilitation Department, IRCCS Bambino Gesù Children’s Hospital, 00163 Rome, Italy;Physical and Rehabilitative Medicine, Department of Health Sciences, University of Eastern Piedmont “A. Avogadro”, 10121 Novara, Italy;Physical and Rehabilitative Medicine, Department of Medical and Surgical Sciences, University of Catanzaro “Magna Graecia”, 88100 Catanzaro, Italy;Rehabilitation Department Versilia Hospital, Versilia Hospital AUSL Toscana Nord Ovest, 55049 Lido di Camaiore, Italy;Section of Rehabilitation, Department of Neuroscience, University General Hospital of Padova, 35128 Padua, Italy;Società Italiana di Medicina Fisica e Riabilitativa (SIMFER), 00198 Rome, Italy;Villa Beretta Rehabilitation Center, Department of Rehabilitation Medicine, Valduce Hospital, 23845 Costa Masnaga, Italy;

关键词: cervical spinal cord injury;    arm function;    exoskeleton;    robot-assisted therapy;    robotic therapy;    rehabilitation;   

DOI  :  10.3390/brainsci11121630

来源: DOAJ

【 摘 要 】

The upper extremities limitation represents one of the essential functional impairments in patients with cervical spinal cord injury. Electromechanics assisted devices and robots are increasingly used in neurorehabilitation to help functional improvement in patients with neurological diseases. This review aimed to systematically report the evidence-based, state-of-art on clinical applications and robotic-assisted arm training (RAT) in motor and functional recovery in subjects affected by cervical spinal cord injury. The present study has been carried out within the framework of the Italian Consensus Conference on “Rehabilitation assisted by robotic and electromechanical devices for persons with disability of neurological origin” (CICERONE). PubMed/MEDLINE, Cochrane Library, and Physiotherapy Evidence Database (PEDro) databases were systematically searched from inception to September 2021. The 10-item PEDro scale assessed the study quality for the RCT and the AMSTAR-2 for the systematic review. Two different authors rated the studies included in this review. If consensus was not achieved after discussion, a third reviewer was interrogated. The five-item Oxford CEBM scale was used to rate the level of evidence. A total of 11 studies were included. The selected studies were: two systematic reviews, two RCTs, one parallel-group controlled trial, one longitudinal intervention study and five case series. One RCT was scored as a high-quality study, while the systematic review was of low quality. RAT was reported as feasible and safe. Initial positive effects of RAT were found for arm function and quality of movement in addition to conventional therapy. The high clinical heterogeneity of treatment programs and the variety of robot devices could severely affect the generalizability of the study results. Therefore, future studies are warranted to standardize the type of intervention and evaluate the role of robotic-assisted training in subjects affected by cervical spinal cord injury.

【 授权许可】

Unknown