Hereditary persistence of fetal hemoglobin

Asian Journal of Transfusion Science

关键词: hereditary persistence of fetal hemoglobin;    heterozygotes;    homozygotes;   

DOI  :  10.4103/ajts.AJTS_71_16

来源: DOAJ

【 摘 要 】

Hereditary persistence of fetal hemoglobin (HPFH) is a benign condition in which significant fetal hemoglobin production continues well into adulthood, disregarding the normal shutoff point after which only adult-type hemoglobin should be produced. The percentage of incorrect expression might be as low as 10%–15% or as high as 100% of the total hemoglobin, usually higher in homozygotes than in heterozygotes. The present case is a typical example of homozygous HPFH.

【 授权许可】

Unknown