Association of accelerometer-measured physical activity with kidney function in a Japanese population: the DOSANCO Health Study

BMC Nephrology

Shiho Amagasa¹  Shigeru Inoue¹  Aya Yoshimura²  Sachiko Sasaki²  Emiko Okada²  Takashi Kimura²  Shigekazu Ukawa²  Aya Tanaka²  Koshi Nakamura²  Akiko Tamakoshi²  Akihiro Imae³  Takafumi Nakagawa⁴ 

[1] Department of Preventive Medicine and Public Health, Tokyo Medical University;Department of Public Health, Hokkaido University Faculty of Medicine;Suttu Municipal Clinic;The Hokkaido Centre for Family Medicine;

关键词: Estimated glomerular filtration rate;    Physical activity;    Sedentary behavior;    Accelerometer;   

DOI  :  10.1186/s12882-021-02635-0

来源: DOAJ

【 摘 要 】

Abstract Background Sedentary behavior and decreased physical activity are associated with reduced kidney function, yet most evidence is based on self-reported physical activity. This study investigated the association between accelerometer-based physical activity level and kidney function in a general Japanese population. Methods A cross-sectional study was conducted in 440 community-dwelling Japanese participants, aged 35–79 years. Time (min/d) was assessed for the following types of physical activity: sedentary behavior, light physical activity (LPA), and moderate-to-vigorous physical activity (MVPA). Kidney function was assessed using estimated glomerular filtration rate (eGFR). A linear regression model was employed to calculate the β coefficient of eGFR for a 60-min/d increase in sedentary behavior and LPA and a 10-min/d increase in MVPA. A logistic regression model was used to calculate the odds ratio for low eGFR (< 60 versus ≥60 mL/min/1.73m2) for a 60-min/d or 10-min/d increase in each physical activity type. Results MVPA time and eGFR were positively associated in both men and women, after adjusting for age, body mass index, and other clinical characteristics (Men: β, 0.91; P = 0.021; Women: β, 0.70; P = 0.034). In women, sedentary behavior and eGFR were inversely associated after adjusting for the same factors (β, − 1.06; P = 0.048). The odds ratio (95% confidence interval) for low eGFR associated with a 60-min increase in sedentary behavior was 1.65 (1.07–2.55) after adjusting for the same factors in women. Conclusion Longer sedentary behavior and shorter MVPA time were associated with lower kidney function in the Japanese population.

【 授权许可】

Unknown