Boosting Recovery During Sleep by Means of Auditory Stimulation

Frontiers in Neuroscience

Sven Leach¹  Elena Krugliakova¹  Jelena Skorucak¹  Reto Huber²  Giulia Da Poian³  Walter Karlen³  Maria Laura Ferster³  Georgia Sousouri³  Sophia Snipes⁴ 

[1]Child Development Centre and Children’s Research Centre, University Children’s Hospital Zurich, University of Zurich, Zurich, Switzerland

[2]Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric Hospital, University of Zurich, Zurich, Switzerland

[3]Mobile Health Systems Lab, Department of Health Sciences and Technology, ETH Zürich, Zurich, Switzerland

[4]Neural Control of Movement Lab, Department of Health Sciences and Technology, ETH Zürich, Zurich, Switzerland

关键词: auditory stimulation;    non-rapid eye movement sleep (NREM);    sleep homeostasis;    recovery;    slow waves;   

DOI  :  10.3389/fnins.2022.755958

来源: DOAJ

【 摘 要 】

Sufficient recovery during sleep is the basis of physical and psychological well-being. Understanding the physiological mechanisms underlying this restorative function is essential for developing novel approaches to promote recovery during sleep. Phase-targeted auditory stimulation (PTAS) is an increasingly popular technique for boosting the key electrophysiological marker of recovery during sleep, slow-wave activity (SWA, 1–4 Hz EEG power). However, it is unknown whether PTAS induces physiological sleep. In this study, we demonstrate that, when applied during deep sleep, PTAS accelerates SWA decline across the night which is associated with an overnight improvement in attentional performance. Thus, we provide evidence that PTAS enhances physiological sleep and demonstrate under which conditions this occurs most efficiently. These findings will be important for future translation into clinical populations suffering from insufficient recovery during sleep.

【 授权许可】

Unknown