Effects of a Multicomponent Exercise Program in Physical Function and Muscle Mass in Sarcopenic/Pre-Sarcopenic Adults

Journal of Clinical Medicine

Kota Tsutsumimoto¹  Takuro Kubozono²  Mitsuru Ohishi²  Yuki Nakai³  Ryoji Kiyama³  Hyuma Makizako³  Kazutoshi Tomioka⁴  Yoshiaki Taniguchi⁴  Ayumi Wada⁴  Nana Sato⁴  Yuto Kiuchi⁴  Toshihiro Takenaka⁵ 

[1] Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Obu 474-5811, Japan;Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan;Department of Physical Therapy, School of Health Sciences, Faculty of Medicine, Kagoshima University, Kagoshima 890-8544, Japan;Graduate School of Health Sciences, Kagoshima University, Kagoshima 890-8544, Japan;Tarumizu Municipal Medical Center Tarumizu Chuo Hospital, Kagoshima 891-2124, Japan;

关键词: muscle strength;    sarcopenia;    resistance training;    randomized controlled trial;   

DOI  :  10.3390/jcm9051386

来源: DOAJ

【 摘 要 】

This study aimed to assess the effects of a multicomponent exercise program on physical function and muscle mass in older adults with sarcopenia or pre-sarcopenia. Moreover, we aim to standardize the exercise program for easy incorporation in the daily life of community-dwelling older adults as a secondary outcome. A single-blind randomized controlled trial was conducted with individuals (≥60 years) who had sarcopenia or pre-sarcopenia (n = 72). Participants were randomly assigned to the exercise and control groups. The exercise program consisted of 12 weekly 60-minute sessions that included resistance, balance, flexibility, and aerobic training. Outcome measures were physical function and muscle mass. Assessments were conducted before and immediately after the intervention. Among the 72 participants (mean age: 75.0 ± 6.9 years; 70.8% women), 67 (93.1%) completed the trial. Group-by-time interactions on the chair stand (p = 0.02) and timed “up and go” (p = 0.01) tests increased significantly in the exercise group. Although the exercise group showed a tendency to prevent loss of muscle mass, no significant interaction effects were observed for cross-sectional muscle area and muscle volume. The 12-week exercise program improved physical function in the intervention group. Although it is unclear whether the program is effective in increasing muscle mass, a multicomponent exercise program would be an effective treatment for physical function among older adults with sarcopenia.

【 授权许可】

Unknown