Stories and Challenges of Genome Wide Association Studies in Livestock — A Review

Asian-Australasian Journal of Animal Sciences

Seung-Hwan Lee¹  Pita Sudrajad²  Hee Seol Kang²  Hyeong Cheol Kim²  Seong Heum Yeon²  Jun Seop Lee²  Chang Gwon Dang² 

[1] Department of Animal Science and Biotechnology, Chung Nam National University, Daejeon 305-764, .Korea;;

关键词: QTL;    Livestock;    Genome-wide Association;   

DOI  :  10.5713/ajas.14.0715

来源: DOAJ

【 摘 要 】

Undoubtedly livestock is one of the major contributors to the economy of any country. The economic value of livestock includes meat, dairy products, fiber, fertilizer etc. Understanding and identifying the associations of quantitative trait loci (QTL) with the economically important traits is believed to substantially benefit the livestock industry. The past two decades have seen a flurry of interest in mapping the QTL associated with traits of economic importance on the genome. With the availability of single nucleotide polymorphism chip of various densities it is possible to identify regions, QTL and genes on the genome that explain the association and its effect on the phenotype under consideration. Remarkable advancement has been seen in genome wide association studies (GWAS) since its inception till the present day. In this review we describe the progress and challenges of GWAS in various livestock species.

【 授权许可】

Unknown