Bridge to diagnosis: The use of extracorporeal membrane oxygenation in a child with interstitial lung disease secondary to clinically amyopathic dermatomyositis

Journal of Pediatric Surgery Case Reports

Eva W. Cheung¹  Amy J. Starr²  Steven Stylianos³  William Middlesworth³  Roberto Mejias³  Shunpei Okochi³  Christine Schad³  Angela Kadenhe-Chiweshe³ 

[1] Division of Pediatric Cardiology, Morgan Stanley Children's Hospital, New York, NY, USA;Division of Pediatric Rheumatology, Morgan Stanley Children's Hospital, New York, NY, USA;Division of Pediatric Surgery, Morgan Stanley Children's Hospital, New York, NY, USA;

关键词: Extracorporeal membrane oxygenation;    Clinically amyopathic dermatomyositis;    Acute respiratory distress;   

DOI  :  10.1016/j.epsc.2016.04.009

来源: DOAJ

【 摘 要 】

Clinically amyopathic dermatomyositis (CADM), a subtype of dermatomyositis (DM), is characterized as having the classic cutaneous manifestations of DM but with little or no evidence of myositis. The presence of anti-melanoma differentiation associated gene 5 (anti-MDA-5) autoantibodies, in the setting of CADM, is associated with rapidly progressive interstitial lung disease (RPILD). The use of extracorporeal membrane oxygenation (ECMO) in patients with RPILD has been well described in adults, but not in children. Herein we present a 14-year old patient with interstitial lung disease, initially of unknown etiology, whom we supported with ECMO in the acute phase of her illness for nearly two months during which the diagnosis of anti-MDA-5 dermatomyositis was established.

【 授权许可】

Unknown