Phytochemical study of Illicium angustisepalum and its biological activities

Acta Pharmaceutica Sinica B

Chun-Tao Che¹  Ming Zhao¹  Karina M. Szymulanska-Ramamurthy¹ 

[1] Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago 60612, USA;

关键词: Illicium angustisepalum;    Chemical ingredients;    Antibacterial;    Neuroprotection;    Anti-acetylcholinesterase;   

DOI  :  10.1016/j.apsb.2017.06.002

来源: DOAJ

【 摘 要 】

Sixteen compounds, including two new natural products (1 and 2), were obtained from the twigs of Illicium angustisepalum. The structures were elucidated based on NMR, MS, IR data and optical rotation values. Compounds 4, 5, 6 and 8 displayed moderate antibacterial activities against clinical isolates; compounds 4, 5, 8, 9 and 15 protected neural cells against oxidative stress; and compounds 10 and 14 exhibited anti-acetylcholinesterase activity.

【 授权许可】

Unknown