An improved and sustainable approach for the synthesis of α,β-dibromo ketones using ceric ammonium nitrate and ammonium bromide

Green Processing and Synthesis

Kulkarni Pramod S.¹  Totawar Balaji B.²  Pudukulathan Zubaidha K.² 

[1] Department of Chemistry, Hutatma Rajguru Mahavidyalaya Rajgurunagar, Pune, Maharashtra 410505, India;School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded, Maharashtra 431606, India;

关键词: α,β-unsaturated ketone;    ammonium bromide;    bromination;    can;    dibromo ketone;    grinding;    sustainable approach;   

DOI  :  10.1515/gps-2015-0097

来源: DOAJ

【 摘 要 】

A simple and environmentally benign procedure for the bromination of substituted α,β-unsaturated ketones in good yield has been described using ammonium bromide as a brominating agent and ceric ammonium nitrate (CAN) as a single-electron oxidant to afford α,β-dibromoketones. The reaction involves C-Br bond formation by radical method generated by CAN. The reaction can be carried out by either at room temperature, stirring in solvent CH3CN or under aqueous moist condition with few drops of water by manual grinding in a mortar and pestle.

【 授权许可】

Unknown