Fatal native aortic valve fungal endocarditis caused by Aspergillus flavus: A case report

IDCases

Mohammed A. Alamin¹  Abdulaziz Alkhulaifi²  Dawoud I. Al Kindi³  Ammar M. Kanaan⁴  Abdulrahman F. Al-Mashdali⁴ 

[1]Correspondence to: Department of Internal Medicine, Hamad Medical Corporation (HMC), Al Rayyan Road, P.O. Box 3050, Doha, Qatar.

[2]Department of Cardiology, Heart Hospital, Hamad Medical Corporation, Doha, Qatar

[3]Department of Cardiothoracic Surgery, Heart Hospital, Hamad Medical Corporation, Doha, Qatar

[4]Department of Internal Medicine, Hamad Medical Corporation, Doha, Qatar

关键词: Endocarditis;    Fungal;    Aspergillus flavus;    Diabetes mellitus;    Case report;   

DOI  :  

来源: DOAJ

【 摘 要 】

Fungal endocarditis is a rare condition, specifically in immunocompetent patients. Aspergillus species are the etiology in less than 30% of the cases. Moreover, Aspergillus flavus endocarditis is extremely rare and reported in only 7% of the total Aspergillus endocarditis cases. The most common predisposing factors are immunocompromised state, prosthetic valve, and previous cardiac surgery. In most cases, the diagnosis is delayed and occasionally missed. Prompt medical management combined with early surgical intervention is recommended once the diagnosis is established since the mortality rate is nearly 100% without surgical intervention. We report a rare and fatal case of native aortic valve endocarditis in a 49 years old diabetic patient who presented with fever and abdominal pain, complicated by multiple septic embolizations (splenic infarction, cerebral emboli, and limbs ischemia), and in which A. flavus was confirmed post mortem.

【 授权许可】

Unknown