Lanthanide-Doped Nanoparticles for Diagnostic Sensing

Nanomaterials

Aeju Lee¹  Yong Il Park²  Song Yeul Lee²  Min Lin³ 

[1] International Research Organization for Advance Science and Technology (IROAST), Kumamoto University, Kumamoto 860-8555, Japan;School of Chemical Engineering, Chonnam National University, Gwangju 61186, Korea;The Key Laboratory of Biomedical Information Engineering, Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, China;

关键词: lanthanide;    upconversion;    nanoparticles;    diagnostics;    sensing;   

DOI  :  10.3390/nano7120411

来源: DOAJ

【 摘 要 】

Lanthanide-doped nanoparticles exhibit unique optical properties, such as a long luminescence lifetime (up to several milliseconds), sharp emission peaks, and upconversion luminescence over the range of wavelengths from near-infrared to visible. Exploiting these optical properties, lanthanide-doped nanoparticles have been widely utilized for cellular and small animal imaging with the absence of background autofluorescence. In addition, these nanoparticles have advantages of high signal-to-noise ratio for highly sensitive and selective diagnostic detection. In this review, we summarize and discuss recent progress in the development of highly sensitive diagnostic methods using lanthanide-doped nanoparticles. Combined with a smartphone, portable luminescence detecting platforms could be widely applied in point-of-care tests.

【 授权许可】

Unknown