The COVID-19 Pandemic: a Study on Its Impact on Patients with Dystonia and Related Conditions Treated with Botulinum Toxin in a Tertiary Centre in Romania

Modern Medicine

Liviu COZMA¹  Iulia MITREA¹  Ovidiu-Lucian BAJENARU¹  Bogdan Ovidiu POPESCU¹  Delia TULBA¹  Natalia BLIDARU²  Mioara AVASILICHIOAEI²  Sorina NECULAI² 

[1] Department of Clinical Neurosciences, Faculty of Medicine, „Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania;Department of Neurology, Colentina Clinical Hospital, Bucharest, Romania;

关键词: dystonia;    hemifacial spasm;    botulinum toxin;    sars-cov-2;    covid-19;    vaccine;   

DOI  :  https://doi.org/10.31689/rmm.2021.29.2.105

来源: DOAJ

【 摘 要 】

Background and Objectives: The COVID-19 pandemic triggered significant delays in the treatment of people with movement disorders who depend on face-to-face clinic encounters for receipt of their regular botulinum toxin injections. Against this background, it was the aim of this study to look into pandemic-related characteristics of patients with dystonia and hemifacial spasm treated with botulinum toxin at a tertiary centre in Romania and identify potential correlations between delays in treatment and health perceptions. Materials and Methods: A cross sectional, questionnaire-based, study was conducted between May-September 2021 on the 175 patients in the centre’s botulinum toxin database. Results: Of the 90 patients who qualified for inclusion most were late middle-aged females with long-standing dystonia, of which torticollis and blepharospasm were the most common phenotypes. Treatment was delayed by an average of 8.5 months, whereas the overall quality-of-life health score was 61.1, with 60% of respondents rating themselves above 50. No statistically significant correlation was identified between delays in treatment and overall health scores. Instead, statistically significant differences were uncovered based on type of disorder (dystonia vs. hemifacial spasm). Conclusion: The results of this study may go on to show that, in the event of similar pandemic surges, patient micromanagement by type of disorder may be part of a well-balanced restriction-cum-access health policy.

【 授权许可】

Unknown