Active site-specific quantum tunneling of hACE2 receptor to assess its complexing poses with selective bioactive compounds in co-suppressing SARS-CoV-2 influx and subsequent cardiac injury

Journal of Advanced Veterinary and Animal Research

Samin Anis¹  Farzana Alam Arshe²  Fauzia Haque²  Tanzila Ismail Ema²  Mohammad Tanbir²  Shahlaa Zernaz Ahmed²  Arysha Alif Khan²  Afsana Masud²  Fatiha Faheem Taheya²  Dipta Dey³  Sharmin Akter⁴  Md. Abdur Rashid Mia⁵  Salauddin Al Azad⁶  Md. Saddam Hossen⁷  Sabrina Jahan Mily⁸  Md. Al Hasibuzzaman⁹  Tanzina Sharmin Nipun^1,10 

[1] Chattogram Maa-O-Shishu Hospital Medical College, University of Chittagong, Chattogram, Bangladesh;Department of Biochemistry and Microbiology, North South University, Dhaka, Bangladesh;Department of Biochemistry and Molecular Biology, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalgonj, Bangladesh.;Department of Genetics and Plant Breeding, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh;Department of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia;Fermentation Engineering Major, School of Biotechnology, Jiangnan University, Wuxi, PR China;Microbiology Major, Faculty of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, PR China;Ministry of Health, People’s Republic of Bangladesh, Dhaka, Bangladesh;School of Medicine, Ningbo University, Ningbo City, PR China;Department of Pharmaceutical Chemistry, Faculty of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia;

关键词: sars-cov-2;    quantum tunneling;    hace2 receptor;    supramolecular docking;    molecular dynamic;    simulation;    drug design;    cardiac injury;   

DOI  :  10.5455/javar.2021.h544

来源: DOAJ

【 授权许可】

Unknown