Relapse of Sulfasalazine-Induced DRESS Syndrome Following the Administraton of Contrast Media: A Case Report

Case Reports in Clinical Practice

Hamidreza Taghvaye-Masoumi¹  Malihe Khosravi-Khezri²  Niayesh Mohebbi³  Mona Talaschian⁴ 

[1] Department of Clinical Pharmacy, Faculty of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.;Department of Clinical Pharmacy, Hasheminejad Kidney Center, Iran University of Medical Sciences, Tehran, Iran.;Department of Clinical Pharmacy, Schoolof Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.;Department of Internal Medicine, Shariat Hospital, Tehran University of Medical Sciences, Tehran, Iran.;

关键词: Contrast media;    Drug reaction with eosinophilia and systemic symptoms;    Hypersensitivity reactions;    Sulfasalazine;   

DOI  :  10.18502/crcp.v6i3.7121

来源: DOAJ

【 摘 要 】

Sulfasalazine, a non-antibiotic sulfonamide, is associated with severe hypersensitivity reactions, including Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome. We report a case of sulfasalazine-induced DRESS syndrome that relapsed following the administration of visipaque® (iodixanol). Macular rashes, pruritus, and an acute exacerbation of dyspnea were immediately observed after the administration of contrast media. It seems that patients suffering from DRESS syndrome are sensitive to the administration of other new medications with a high possibility of hypersensitive reactions. It can be concluded that iodinated contrast media should be used cautiously in patients with DRESS syndrome.

【 授权许可】

Unknown