Fighting Sarcopenia in Ageing European Adults: The Importance of the Amount and Source of Dietary Proteins

Nutrients

Miriam Capri¹  Aurelia Santoro¹  Claudio Franceschi¹  Giuseppe Battista¹  LisetteC. P. G. M. de Groot²  AgnesA. M. Berendsen²  EdithJ. M. Feskens²  Joanna Kaluza³  Barbara Pietruszka³  Dawid Madej³  Alberto Bazzocchi⁴  Susan Fairweather-Tait⁵  Amy Jennings⁵  Diego Montiel-Rojas⁶  Andreas Nilsson⁶  Fawzi Kadi⁶ 

[1] Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy;Department of Human Nutrition and Health, Wageningen University, 6708WE Wageningen, The Netherlands;Department of Human Nutrition, Warsaw University of Life Sciences-SGGW, 02-776 Warsaw, Poland;Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy;Norwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK;School of Health Sciences, Örebro University, 702 81 Örebro, Sweden;

关键词: elderly;    plant protein;    animal protein;    muscle mass;    macronutrients;    isocaloric substitution;   

DOI  :  10.3390/nu12123601

来源: DOAJ

【 摘 要 】

While an adequate protein intake is important for the maintenance of muscle mass during ageing, the amount and source of protein necessary for optimal prevention of sarcopenia remains to be determined. The present study aimed to investigate the influence of the amount and source of dietary proteins on sarcopenia risk in a cohort of 65–79-year-old European adults within the frame of the NU-AGE study. A total of 986 participants were included in the analysis. Skeletal muscle index (SMI), assessed by dual-energy X-ray absorptiometry (DXA), and handgrip strength (HG) were employed to create a continuous sex-specific sarcopenia risk score (SRS). Total amount together with animal- and plant-derived sources of proteins were obtained from a 7-day food record. Differences in SRS were analysed across groups of total protein intake (<0.8 g/body weight (BW); 0.8–<1.0 g/BW; 1.0–<1.2 g/BW; and ≥1.2 g/BW). The association between SRS and the different sources of protein was assessed using isocaloric substitution models adjusted by demographic, medical, and lifestyle factors. A significant linear dose-response relationship was observed, with a lower SRS linked to higher protein intakes. Based on the isocaloric substitution modelling, a reduced SRS was observed when increasing plant protein to the detriment of animal protein, while holding total protein intake constant. Further, this result remained significant after stratifying the analysis by adherence to different levels of protein intake. Our findings suggest that older adults may benefit from increasing protein intakes above current recommendations. Besides total amount, protein source should be considered when promoting health dietary habits in older adults for the prevention of sarcopenia.

【 授权许可】

Unknown