Acute necrotic hemorrhagic leukoencephalitis related to COVID-19: a report of 2 cases

Radiology Case Reports

Aeed Alaklabi¹  Hanan Alharthi²  Suhayb aldhilan²  Hamid Alam³  Stefan Kristjansson⁴  Alwaleed Alqahtani⁴ 

[1] Corresponding author.;Radiology Department, King Faisal Specialist Hospital, Riyadh, Saudi Arabia;Radiology Department, Prince Sultan Military Medical Hospital, Riyadh, Saudi Arabia;Radiology Department, Security Forces Hospital, Riyadh, Saudi Arabia;

关键词: SARS-COVID2;    COVID-19;    Coronavirus;    Neuroimaging;    Brain;    White matter disease;   

DOI  :  

来源: DOAJ

【 摘 要 】

Acute necrotic hemorrhagic leukoencephalitis (ANHLE) is a subform of acute disseminating leukoencephalitis which is a post viral or vaccination uncommon disease with poor prognosis. Radiological findings include multiple or diffuse lesions involving the white matter and sparing the cortex with or without rim enhancement. In addition to areas of hemorrhages with possible involvement of basal ganglia and thalami. We describe the imaging findings for 2 cases of ANHLE; a 59-years-old male and a 47-years-old female. Both of them were tested positive of SARS-COVID2 with presentation of consciousness loss and respiratory failure. CT and MRI brain show global white matter changes associated with acute hemorrhagic necrosis, although uncommon, are compatible with postviral acute necrotic hemorrhagic leukoencephalitis with end point of death for the first patient and coma for the second patient.

【 授权许可】

Unknown