Sleep disturbances in obsessive-compulsive disorder: influence of depression symptoms and trait anxiety

BMC Psychiatry

Javier Labad¹  Pino Alonso²  Sara Bertolín²  Neus Salvat-Pujol²  Susana Jiménez-Murcia²  Cinto Segalàs²  José M. Menchón²  Virginia Soria²  Eva Real²  Carles Soriano-Mas²  Carmen Monasterio³ 

[1] Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Carlos III Health Institute;Department of Psychiatry, Bellvitge University Hospital. Bellvitge Biomedical Research Institute (IDIBELL), Neurosciences Group - Psychiatry and Mental Health;Multidisciplinary Sleep Unit, Department of Respiratory Medicine, Bellvitge University Hospital. Bellvitge Biomedical Research Institute (IDIBELL), Section of Respiratory Medicine, L’Hospitalet de Llobregat;

关键词: Obsessive-compulsive disorder;    Sleep disorders;    Sleep quality;    Delayed sleep phase disorder;    Depression;    Trait anxiety;   

DOI  :  10.1186/s12888-021-03038-z

来源: DOAJ

【 摘 要 】

Abstract Background Sleep disturbances have been reported in obsessive-compulsive disorder (OCD) patients, with heterogeneous results. The aim of our study was to assess sleep function in OCD and to investigate the relationship between sleep and the severity of obsessive-compulsive (OC) symptoms, depressive symptoms and trait anxiety. Methods Sleep quality was measured in 61 OCD patients and 100 healthy controls (HCs) using the Pittsburgh Sleep Quality Index (PSQI). Multiple linear regression was conducted to explore the association between sleep and psychopathological measures; a mediation analysis was also performed. Results OCD patients showed poor sleep quality and more sleep disturbances compared to HCs. The severity of depression, trait anxiety and OC symptomatology were correlated with poor sleep quality. Multiple linear regression analyses controlling for potential confounders revealed that the severity of depression and trait anxiety were independently related to poor sleep quality in OCD. A mediation analysis showed that both the severity of trait anxiety and depression mediate the relationship between the severity of OC symptoms and poor sleep quality among patients with OCD. Conclusions Our findings support the existence of sleep disturbances in OCD. Trait anxiety and depression play a key role in sleep quality among OCD patients.

【 授权许可】

Unknown