Dissolved Organic Matter Modulates Algal Oxidative Stress and Membrane System Responses to Binary Mixtures of Nano-Metal-Oxides (nCeO2, nMgO and nFe3O4) and Sulfadiazine

Nanomaterials

De-Gao Wang¹  Hao Fang²  Nan Ye²  Yue Meng²  Se Wang²  Fan Zhang²  Zhuang Wang² 

[1]College of Environmental Science and Engineering, Dalian Maritime University, Dalian 116026, China

[2]School of Environmental Science and Engineering, Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control, Nanjing University of Information Science and Technology, Nanjing 210044, China

关键词: nanoparticles;    sulfadiazine;    mixture toxicity;    freshwater algae;    dissolved organic matter;   

DOI  :  10.3390/nano9050712

来源: DOAJ

【 摘 要 】

Joint biomarker responses, oxidative stress and membrane systems, were determined for nano-metal-oxides (nMeO, i.e., nCeO₂, nMgO, and nFe₃O₄) and sulfadiazine (SDZ) exposed at relevant low concentrations to two freshwater microalgae Scenedesmus obliquus and Chlorella pyrenoidosa. The impacts of dissolved organic matter (DOM) on the joint biomarker responses were also investigated. Results indicated that the presence of SDZ significantly decreased the level of intercellular reactive oxygen species (ROS) in the algal cells exposed to each nMeO. Reduction of cell membrane permeability (CMP) and mitochondrial membrane potential (MMP) in the algal cells was observed when the algae were exposed to the mixture of SDZ and the nMeO. The degree of reduction of the ROS level, CMP, and MMP significantly went down with the addition of DOM to a certain extent. Changes in cellular oxidative stress and membrane function depended on the types of both nMeO and algal species. This contribution provides an insight into the hazard assessment of a mixture consisting of emerging contaminants and DOM, as they can coexist in the aquatic environment.

【 授权许可】

Unknown