Evidence for trait related theory of mind impairment in first episode psychosis patients and its relationship with processing speed: a three year follow-up study.

Frontiers in Psychology

Rosa eAyesa-Arriola²  Jose Manuel eRodríguez-Sánchez²  Mar eFatjó-Vilas⁵  Marcos eRios-Lago⁶  Adele eFerro⁸  Benedicto eCrespo-Facorro⁹  Soraya eOtero⁹  Esther eSetién Suero⁹  Karl eNeergaard^1,10 

[1] Institute of Biomedicine of the University of Barcelona (IBUB);Centro Investigación Biomédica en Red de Salud Mental (CIBERSAM);Centro Investigación en Red de Salud Mental de Bizkaia-Osakidetza;Child and Adolescent Psychiatry Unit, Marqués de Valdecilla University Hospital;Faculty of Biology, Universitat de Barcelona;Faculty of Psychology. Universidad de Educación a Distancia (UNED);Fondazione IRCCCS, Granda Ospedale Maggiore Policlinico;InterUniversity Center for Behavioral Neurosciences (ICBN), University of Udine and University of Verona;Marqués de Valdecilla University Hospital, IDIVAL, School of Medicine, University of Cantabria;The Hong Kong Polytechnic University;Unidad de Daño Cerebral. Red Menni de Atención al Daño Cerebral. Hospital Beata María Ana;

关键词: Schizophrenia;    Theory of Mind;    first episode psychosis;    processing speed;    clinical symptoms;   

DOI  :  10.3389/fpsyg.2016.00592

来源: DOAJ

【 摘 要 】

This study aimed to confirm whether first-episode psychosis patients present a stable trait impairment in theory of mind (ToM) and to examine the potential relationship between ToM and clinical symptomatology and neurocognition. Patients with a first episode of psychosis (N = 160) and healthy controls (N = 159) were assessed with an extensive neuropsychological test battery, which included a mental state decoding task known as The Reading the Mind in the Eyes (Eyes test), at baseline and reassessed after 1 and 3 years. The clinical group performed below healthy controls on the Eyes test while not showing test-retest differences between baseline and follow-up administrations. Analyses revealed age, education and premorbid IQ as potential moderators. Poorer performance on the Eyes test was not linked to clinical symptomatology but was associated with greater neurocognitive deficit, particularly related to processing speed. The persistence of ToM deficits in patients suggests that there are trait related mentalising impairments in first episode psychosis. This study shows the influence of processing speed and moderator variables on efficient ToM.

【 授权许可】

Unknown