Intravitreal bevacizumab (avastin) for circumscribed choroidal hemangioma

Indian Journal of Ophthalmology

关键词: Ahmed glaucoma valve;    hypotony;    post-penetrating-keratoplasty glaucoma;    tube extrusion;    scleral patch;    Ranibizumab;    bevacizumab;    choroidal neovascular membrane;    age-related macular degeneration;    intravitreal injection;    central macular thickness;    best corrected visual acuity;    Intravitreal injection;    methotrexate;    pharmacokinetics;    Contrast sensitivity;    diabetes;    glare;    pupil cycle time;    Anemia;    diabetic retinopathy;    microalbuminuria;    severity;    Objective Structured Clinical Examination;    ophthalmology;    undergraduate;    Anisometropia;    anisometropic amblyopia;    fusion;    stereopsis;    Traumatic cataract;    Birmingham Eye Trauma Terminology System;    India;    cataract surgery;    Children with learning disability;    ocular disorders;    refractive errors;    special needs;    Charles Bonnet syndrome;    dementia;    hallucinations;    pregabalin;    Ocular surface reconstruction;    Steven-Johnson syndrome;    superficial keratectomy;    Choroidal melanoma;    hard exudates;    lipid exudation;    Donor sclera;    globe rupture;    scleral patch graft;    Eyelid;    Miragel;    retinal detachment;    scleral buckle;    Angiitis;    Behcet disease;    neuroretinitis;    Bevacizumab;    choroidal neovascularization;    intravitreal injection;    myopia;    photodynamic therapy;    ranibizumab;    triamcinolone acetonide;    vascular endothelial growth factor;    Enucleation;    immunohistochemistry;    massive retinal gliosis;    Bevacizumab;    circumscribed choroidal hemangiomas;    photodynamic therapy;    transpupillary thermotherapy;   

DOI  :  10.4103/0301-4738.81051

来源: DOAJ

【 摘 要 】

Circumscribed choroidal hemangiomas are rare ophthalmic entities that cause diminution in vision due to accumulation of subretinal and/or intraretinal fluid in the macular area. Various treatment options ranging from conventional laser to photodynamic therapy have been employed to destroy the tumor and reduce the exudation; however, either the inability to penetrate through the exudative fluid or the collateral retinal damage induced by these treatment modalities make them unsuitable for lesions within the macula. We evaluated the role of intravitreal bevacizumab, a pan-vascular endothelial growth factor (VEGF) inhibitor, in reducing the sub- and intraretinal fluid in three patients with circumscribed choroidal hemangiomas. All the patients had complete resolution of the serous retinal detachment that was maintained till at least 12 months after the first injection. Intravitreal bevacizumab may be used in combination with thermal laser or photodynamic therapy in treating circumscribed choroidal hemangiomas with subretinal fluid.

【 授权许可】

Unknown