Role of Cachexia and Fragility in the Patient Candidate for Cardiac Surgery

Nutrients

CarmelaRita Balistreri¹  Dario Buioni²  MariaSabrina Ferrante²  Giovanni Ruvolo²  Paolo Nardi²  Claudia Altieri²  Calogera Pisano²  Laura Asta²  Daniele Trombetti²  Fabio Bertoldo²  Calogero Foti³  Daniele Polisano³ 

[1] Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, 90133 Palermo, Italy;Department of Cardiac Surgery, Tor Vergata University Hospital, 00133 Rome, Italy;Physical and Rehabilitation Medicine, Tor Vergata University of Rome, 00133 Rome, Italy;

关键词: frailty;    vascular aging;    age related syndrome;    sarcopenia;    malnutrition;   

DOI  :  10.3390/nu13020517

来源: DOAJ

【 摘 要 】

Frailty is the major expression of accelerated aging and describes a decreased resistance to stressors, and consequently an increased vulnerability to additional diseases in elderly people. The vascular aging related to frail phenotype reflects the high susceptibility for cardiovascular diseases and negative postoperative outcomes after cardiac surgery. Sarcopenia can be considered a biological substrate of physical frailty. Malnutrition and physical inactivity play a key role in the pathogenesis of sarcopenia. We searched on Medline (PubMed) and Scopus for relevant literature published over the last 10 years and analyzed the strong correlation between frailty, sarcopenia and cardiovascular diseases in elderly patient. In our opinion, a right food intake and moderate intensity resistance exercise are mandatory in order to better prepare patients undergoing cardiac operation.

【 授权许可】

Unknown