A Review on (Hydro)Porphyrin-Loaded Polymer Micelles: Interesting and Valuable Platforms for Enhanced Cancer Nanotheranostics

Pharmaceutics

Marta Pineiro¹  NelsonA. M. Pereira¹  ArturJ. M. Valente¹  BrunoF. O. Nascimento¹  TeresaM. V. D. Pinho e Melo¹ 

[1] CQC and Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal;

关键词: nanotheranostics;    photodynamic therapy;    porphyrin;    micelles;    nanoparticles;   

DOI  :  10.3390/pharmaceutics11020081

来源: DOAJ

【 摘 要 】

Porphyrins are known therapeutic agents for photodynamic therapy of cancer and also imaging agents for NIR fluorescence imaging, MRI, or PET. A combination of interesting features makes tetrapyrrolic macrocycles suitable for use as theranostic agents whose full potential can be achieved using nanocarriers. This review provides an overview on nanotheranostic agents based on polymeric micelles and porphyrins developed so far.

【 授权许可】

Unknown