Activity of keloids evaluated by multimodal photoacoustic/ultrasonic imaging system

Photoacoustics

Yuxin Jiang¹  Nanze Yu²  Xiao Long²  Youbin Wang²  Ruojiao Wang³  Meng Yang³  Chenyang Zhao³  Yu Xia³  Sirui Liu³  Cheng Chen³  Jie Sun⁴  Fang Yang⁴  Zhao Ling Lu⁵ 

[1] Corresponding authors at: Department of Ultrasonography, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Address: No.1, Shuaifuyuan, Dongcheng District, Beijing, China.;Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;Department of Ultrasonography, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, China;Mindray North American Innovation Center, San Jose, CA, United States;

关键词: Keloids;    Ultrasound;    Photoacoustic imaging;    Vancouver Scar Scale;   

DOI  :  

来源: DOAJ

【 摘 要 】

Multiple objective assessments have been used to assess the activity of keloids to compare different therapeutic regimens and facilitate the best individual treatment choice for patients, but none of them are standardized. A multimodal photoacoustic/ultrasonic (PA/US) imaging system, including photoacoustic imaging, elastography, ultra-micro-angiography, and conventional US technologies (gray scale US, color Doppler US, and power Doppler US), was applied to evaluate keloids by a radiologist. Growing stages were defined by patients, and Vancouver Scar Scale (VSS) was assessed by a plastic surgeon. A comprehensive model based on multimodal ultrasound parameters (poor-echo pattern, high vascular density, decreased elasticity, and low SO2 within the keloid) and VSS might be a potential indicator of active keloids, comparing with VSS alone. The multimodal PA/US imaging system could be a promising technique for keloids assessment.

【 授权许可】

Unknown