Towards integrated surveillance of zoonoses: spatiotemporal joint modeling of rodent population data and human tularemia cases in Finland

BMC Medical Research Methodology

A. Lawson¹  C. Rotejanaprasert²  H. Rossow³  J. Sane⁴  H. Henttonen⁵  O. Huitu⁵  V. J. Del Rio Vilas⁶ 

[1] Department of Public Health Sciences, Medical University of South Carolina;Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University;Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki;National Institute for Health and Welfare;Natural Resources Institute Finland;School of Veterinary Medicine, University of Surrey;

关键词: Surveillance integration;    Joint diseases modeling;    Zoonoses;    Tularemia;    Finland;   

DOI  :  10.1186/s12874-018-0532-8

来源: DOAJ

【 摘 要 】

Abstract Background There are an increasing number of geo-coded information streams available which could improve public health surveillance accuracy and efficiency when properly integrated. Specifically, for zoonotic diseases, knowledge of spatial and temporal patterns of animal host distribution can be used to raise awareness of human risk and enhance early prediction accuracy of human incidence. Methods To this end, we develop a spatiotemporal joint modeling framework to integrate human case data and animal host data to offer a modeling alternative for combining multiple surveillance data streams in a novel way. A case study is provided of spatiotemporal modeling of human tularemia incidence and rodent population data from Finnish health care districts during years 1995–2012. Results Spatial and temporal information of rodent abundance was shown to be useful in predicting human cases and in improving tularemia risk estimates in 40 and 75% of health care districts, respectively. The human relative risk estimates’ standard deviation with rodent’s information incorporated are smaller than those from the model that has only human incidence. Conclusions These results support the integration of rodent population variables to reduce the uncertainty of tularemia risk estimates. However, more information on several covariates such as environmental, behavioral, and socio-economic factors can be investigated further to deeper understand the zoonotic relationship.

【 授权许可】

Unknown