Differential Sensing of Antibiotics Using Metal Ions and Gold Nanoclusters Based on TMB–H2O2 System

Chemosensors

Min Zhang¹  Jingxia Yang¹  Jinjie Wang¹  Yunjing Shi¹  Yue Hu¹  Suqin Liu¹ 

[1] College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, 333 Longteng Road, Shanghai 201620, China;

关键词: gold nanocluster;    antibiotic;    colorimetric detection;    linear discriminant analysis;    multiplex detection;   

DOI  :  10.3390/chemosensors10060222

来源: DOAJ

【 摘 要 】

In the water system, antibiotic pollution significantly impacts the human body and the environment. Therefore, it is essential to quickly identify the types of antibiotics in the system and detect their concentration. It has been reported that many metal ions interact with antibiotics, and some of them can also change the enzyme-like catalytic properties of gold clusters (AuNCs). In the experiments, we found significant differences in the experimental results when different antibiotics and metal ions were placed in a TMB-H₂O₂ system with AuNCs as catalysts. Based on this result, we devised a simple and sensitive colorimetric method for the simultaneous detection of multiple antibiotics using AuNCs-metal ions as the sensor, a multifunctional microplate detector as the detection instrument, and LDA as the analytical method. This method was successfully applied for the identification of antibiotics and the detection of their concentrations in river water.

【 授权许可】

Unknown