Allostatic load, unhealthy behaviors, and depressive symptoms in the Hispanic Community Health Study/Study of Latinos

SSM: Population Health

Linda C. Gallo¹  Frank C. Bandiera¹  Saida I. Coreas²  Christian R. Salazar²  Rosalba Hernandez³  Krista M. Perreira⁴  Shakira F. Suglia⁵  Gregory A. Talavera⁶  Carmen R. Isasi⁷  Erik J. Rodriquez⁷  Martha L. Daviglus⁸  Eliseo J. Pérez-Stable⁹  Frank Penedo^1,10 

[1] 3 Center Drive, Bethesda, MD, 20892-0311, USA;National Heart, Lung, And Blood Institute;Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY, 10461, USA;;Department of Epidemiology &Department of Psychology, San Diego State University, 780 Bay Boulevard Suite 200, Chula Vista, CA, 91910, USA;Division of Behavioral and Social Research, National Institute on Aging, 31 Center Drive, Bethesda, MD, 20892-2292, USA;Division of Intramural Research;Rollins School of Public Health, Emory University, 201 Dowman Drive, Atlanta, GA, 30322, USA;School of Medicine, University of North Carolina, 333 South Columbia Street, Chapel Hill, NC, 27599-7240, USA;UC Irvine Institute for Memory Impairment and Neurological Disorders, University of California, Irvine, 3227 Biological Sciences III, Irvine, CA, 92697, USA;

关键词: Stress;    Physiological;    Allostasis;    Health behavior;    Depression;    Hispanic americans;   

DOI  :  

来源: DOAJ

【 摘 要 】

Background: The Environmental Affordances Model (EAM) proposes that the effects of chronic stress on depression are moderated by unhealthy behaviors and race/ethnicity. The unique social structures and contexts of Hispanics/Latinos in the U.S. may influence such relationships. This study evaluated whether unhealthy behaviors weakened the relationship between allostatic load, a measure of chronic stress, and future elevated depressive symptoms among Hispanic Community Health Study/Study of Latinos participants. Methods: Longitudinal data (2008–2011 and 2014–2017) from 11,623 participants were analyzed. The exposure was allostatic load, an index of twelve established biomarkers categorized using clinically relevant cut points, at Visit 1. Elevated depressive symptoms were operationalized as a score of ≥10 (out of 30) on the CES-D 10 at Visit 2. An index of unhealthy behaviors, with one point each for cigarette smoking, excessive/binge drinking, sedentary behavior, and poor diet quality at Visit 1, was examined as an effect modifier. Multivariable logistic regression, in the overall sample and among Mexicans specifically and adjusted for demographic characteristics and elevated depressive symptoms at Visit 1, was used to model allostatic load, unhealthy behavior index (range: 0–4), and their interaction in relation to elevated depressive symptoms at Visit 2. Results: Overall, greater allostatic load was associated with higher odds of elevated depressive symptoms after at least 6 years (aOR = 1.06, 95% CI = 1.01, 1.10). Overall, individuals with greater allostatic load and an unhealthy behavior index = 1, compared to those with an unhealthy behavior index = 0, had lower odds of elevated depressive symptoms at follow-up (aβ = −0.065, 95% CI = −0.12, −0.007). Conclusions: The relationship between chronic stress and depression was partially moderated among Hispanics/Latinos who engaged in unhealthy behavior, which may have reduced their risk of elevated depressive symptoms given more chronic stress.

【 授权许可】

Unknown