Influenza B Viruses with Mutation in the Neuraminidase Active Site, North Carolina, USA, 2010–11

Emerging Infectious Diseases

关键词: zanamivir;    oseltamivir;    peramivir;    neuraminidase inhibitor;    viruses;    North Carolina;   

DOI  :  10.3201/eid1711.110787

来源: DOAJ

【 摘 要 】

Oseltamivir is 1 of 2 antiviral medications available for the treatment of influenza B virus infections. We describe and characterize a cluster of influenza B viruses circulating in North Carolina with a mutation in the neuraminidase active site that may reduce susceptibility to oseltamivir and the investigational drug peramivir but not to zanamivir.

【 授权许可】

Unknown