Intra-Articular Injections in Knee Osteoarthritis: A Review of Literature

Journal of Functional Morphology and Kinesiology

Salvatore Cannavò¹  Matteo Turchetta¹  Vito Pavone¹  Gianluca Testa¹  Annalisa Culmone¹  Serena Maria Chiara Giardina¹  Andrea Vescio¹ 

[1] Department of General Surgery and Medical Surgical Specialties, Section of Orthopaedics and Traumatology, P.O. “Policlinico Gaspare Rodolico”, University of Catania, 95123 Catania, Italy;

关键词: knee osteoarthritis;    injection therapy;    intra-articular injections;    corticosteroids;    hyaluronic acid;    platelet-rich plasma;   

DOI  :  10.3390/jfmk6010015

来源: DOAJ

【 摘 要 】

Knee osteoarthritis (OA) is a chronic, degenerative, and progressive disease of articular cartilage, producing discomfort and physical disability in older adults. Thirteen percent of elderly people complain of knee OA. Management options for knee OA could be divided into the following categories: conservative, pharmacological, procedural, and surgical. Joint replacement is the gold standard, reserved for severe grades of knee OA, due to its complications rate and increased risk of joint revision. A nonsurgical approach is the first choice in the adult population with cartilage damage and knee OA. Yearly, more than 10% of knee OA-affected patients undergo intra-articular injections of different drugs, especially within three months after OA diagnosis. Several molecules, such as corticosteroids injection, hyaluronic acid (HA), and platelet-rich plasma (PRP), are managed to reduce the symptoms of patients with knee OA. The aim of this review was to offer an overview of intra-articular injections used for the treatment of OA and report the conventional pharmacological products used.

【 授权许可】

Unknown